• Reece Poole posted an update 2 months ago

    A variety of performance-based tests are used clinically and in research to measure mobility. The timed up-and-go test (TUG) is among the most frequently used. The TUG measures the time taken to rise from a seated position, walk 3 m at a natural pace, walk back to the chair, and sit down. The test requires only a stopwatch and a chair and is easy…[Read more]

  • Reece Poole posted an update 2 months ago

    Optics, vacuum chamber & cryostatAs shown in Fig. 2, the set-up is a removable extension of the FTIR Bruker IFS 125 HR spectrometer station. This interferometer equips the B branch dedicated to condensed UNC 0642 studies of the AILES beamline. The HPLT compartment consists in a vacuum chamber made of aluminium, obtained from drilling a single…[Read more]

  • Reece Poole posted an update 2 months ago

    Conflict of interestAcknowledgementsThe authors thank Katharina Hufgard, Jacqueline Wax, Heike Schreier and Beate Stirzel for excellent technical assistance. This work was funded by the German Federal Ministry of Education and Research (BMBF) by the MedVet-Staph programme through the German Aerospace Center (DLR), grant numbers 01KI1014E (WZ),…[Read more]

  • AcknowledgmentsThis study was support by the research grants CMFHR10320 and CMFHR10472 from Chi Mei Medical Center, Tainan, Taiwan.IntroductionOral submucous fibrosis (OSF) is a chronic, insidious disease that affects the lamina propria of oral mucosa. Areca quid chewing is an important risk factor for the pathogenesis of OSF. Arecoline, a major…[Read more]

  • ConclusionThis study showed that MRSP isolates from clinical cases in individual dogs and cats in Thailand are multi-resistant, harbour the same resistance genes and have similar characteristics as isolates from Europe and from North America. As seen before, MRSP isolates compared to other methicillin-resistant staphylococci more likely harbour…[Read more]

  • Results and discussionMaterials and methodsAcknowledgementsThe authors acknowledge the support of the National Science Foundation (MCB1408217 to B.A.F).IntroductionSeveral members in the Arenaviridae family cause hemorrhagic fever (HF) disease in humans (Buchmeier et al., 2007; McCormick and Fisher-Hoch, 2002). Thus, Lassa (LASV) in West Africa…[Read more]

  • In Croatia, B. suis is present in both domestic and wild populations in virtually all counties where pigs are bred. In fact, Croatia was the first European country where B. suis biovar 3 infection was detected in horses, swine and wild boars. The animals most frequently infected are swine in extensive production, since the high density of animals…[Read more]

  • In a report of quality of life in patients with intermittent AF, AF patients were either significantly worse or as impaired as either PTCA or post-MI patients on all domains of the SF-36. Similarly, AF was associated with modestly impaired quality of life in Taiwanese patients, measured by EQ-5D visual analogue scale.ClassificationsA variety of…[Read more]

  • AcknowledgmentsIntroductionPeste des petits ruminants virus (PPRV), a Morbillivirus, causes an acute, highly contagious disease of domestic and wild small ruminants characterized by respiratory and gastrointestinal pathology (Munir, 2013). PPRVs have been classified into four lineages based on variable order AM251 of the nucleoprotein (NP)…[Read more]

  • The N of VSV is always in an oligomeric state when associated with RNA. Based on the 2.9-Å structure of the N–RNA complex, the extensive intermolecular interactions of N monomers exist and emphasize the importance of these interactions in the formation of a stable N–RNA complex (Green et al., 2006). Within these intermolecular interactions, the…[Read more]

  • No antimicrobials are currently labelled for marine mammal use because none has been licensed by the regulatory agencies (such as the US Food and Drug Administration or the European Medicines Agency). Most of the available data come from clinicians and are largely based on empirical trials and, in very few cases, on pharmacokinetic (PK) data…[Read more]

  • Consistent with previous infection studies (von Recum-Knepper et al., 2015; Twu et al., 2007; Kuo and Krug, 2009) and in vitro binding assays, we show that rIAV encoding NS1-wt (F103+M106) replicates to a higher titer at 36 and 48h post-infection in comparison to rIAVs encoding NS1-M106I/F103L+M106I, in A549 Dioscin and in non-immortalized…[Read more]

  • Molecular geneticsGenetic correlations with milk productionThere are more DA-affected cows on farms that have a high production level, but among individual animals, a correlation between milk production and DA has not been validated (Rohrbach et al., 1999; Wolf et al., 2001). Hamann et al. (2004) were unable to determine significant genetic…[Read more]

  • ConclusionsMolecular docking results showed stronger binding of the PCA (−3.23kcal/mol) to the hydrophobic pocket than that of the dioxane (−2.86kcal/mol). The binding constant (KD) calculated using isothermal titration calorimetry (ITC) for dioxane and PCA were 80µM and 61µM respectively confirming the results of molecular docking. The binding…[Read more]

  • On the other hand, DN T cells seem to act as villains of the immune system in the CSF of dogs in this study by promoting inflammation, considering the positive correlation observed between the intensity of inflammation in the subependymal area and the proportion of DN T cells of the CSF. These cells produce inflammatory cytokines, such as IL-17…[Read more]

  • Using daily average to approximate temperature experienced by vectors and vector-borne pathogens ignores biological effects of fluctuating temperature as well as mathematical discrepancies apparent in prediction models scaled to finer resolutions. Assuming an environment of constant temperature is also unrealistic given that mosquitoes move…[Read more]

  • Amyloid fibrils are β-sheet-rich protein aggregates that are strongly associated with various neurodegenerative diseases [64]. TERS studies of insulin fibrils revealed that their surface is heterogeneous from the viewpoint of both protein secondary structure and amino diprenorphine composition (Fig. 4) [57,65]. It was shown that only about…[Read more]

  • While analyzing the results of experimental work, we should note that earlier in a number of papers [12,63,64] an assumption was made, based on the analysis of experimental data, that the whole series of bands in IR and Raman spectra are in either way caused by the stretching vibrations of OH bonds. But later those authors either assigned one of…[Read more]

  • Microarray analyses and spa typing showed a clear discrimination between MSSA and MRSA originating from the sows of our study. On the one hand MSSA found in sows mainly belonged to CC9 associated spa types (t337, t1430, and t13816). Other authors confirm these findings but did also detect t011 and t034 MSSA in pigs, both belonging to CC398 (Hasman…[Read more]

  • Reece Poole posted an update 3 months ago

    The country’s banking sector although has been recognized for its rapid growth, efficiency, promotion of professionalism and low cost products and services, the sector has been on the other hand engulfed by dilemma of high interest spread, one reason behind higher profitability of banks.Literature reviewVarious approaches have been employed to…[Read more]

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